AbbVie Senior Scientist I, Manufacturing Sciences in Worcester, Massachusetts
Senior Scientist I, Manufacturing Sciences
USA, Massachusetts, Worcester
Research & Development
We are seeking a highly-motivated Senior Scientist/Engineer to join our Downstream group in the Manufacturing Sciences department at AbbVie Bioresearch Center located in Worcester, MA. As part of the Operation Science & Technology organization, our group is responsible for downstream process development, characterization and validation of late clinical stage and commercial biologic products. We provide manufacturing support and co-author regulatory filings. The candidate is expected to devise and implement protein purification strategies to solve complex challenges across the AbbVie pipeline. The candidate should have a solid understanding of protein chemistry and knowledge of purification. The candidate should be able to work independently while contributing in a team environment, and can productively manage several projects simultaneously in a dynamic and rapidly evolving project landscape.
Key Responsibilities Include:
Work independently on the design, execution, and interpretation of resultsof process development and process characterization experimental studies
Identify, evaluate, and develop innovative technologies within thefield of downstream processing to improve process efficiency, robustnessand product quality.
Lead technology and process transfer to pilot lab and GMP plants.
Solve technical issues and support GMP manufacturing
Participate in cross-functional team and author/review/defend CMCsections of regulatory filings.
Author technical reports and other documents independently
Interact with cross-functional groups (e.g. discovery, processsciences, manufacturing, quality, regulatory)
Author peer-reviewed articles and patent. Present original work in conferences.
BS, MS, or PhD in Chemical or Biochemical Engineering, Biochemistry,or related field with 10+ years (BS), 8+ years (MS), or 0-2 years (PhD), relevant academic and/or pharmaceuticalindustry experience.
Solid understanding of protein chemistry and biologic processdevelopment
Strong written and oral communication skills and the ability tocontribute in a multi-disciplinary environment are essential.
Demonstrated problem-solving skills and capability to overcome complexedissues.
Excellent written and oral presentation skills.
Solid understanding proteincharacterization methodologies
Strong interest and knowledge in biochemicalprocess modeling and/or multivariate data analytics
Equal Opportunity Employer Minorities/Women/Veterans/Disabled