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System One Scientist/Process Engineer - Cell Culture in Waltham, Massachusetts

Scientist/Process Engineer - Cell Culture Degree/Experience(any of the below are applicable):

  • Degree in chemical engineering, biochemistry, or applicable fields

  • BS w/ 8 yrs. of industry exp. in a process engineering or application development setting

  • MS w/ 4+ yrs. industry exp. in a process engineering or application development setting

  • PhD w/ 2+ yrs. industry exp. in a process engineering or application development setting


  • Extensive understanding of upstream process development, sterilization processes intensified applications, and BR engineering principles

  • Experienced hands-on work in setting up a lab and bench-scale bioreactors, culturing cells, and optimizing feeding and perfusion strategies

    "Nice Haves":

  • Exp. with gene therapy applications and viral vaccines would be a plus

  • Exp. with continuous bioprocessing is desirable but not necessary


  • Will be a scientific leader in engineering principles to operate bioreactors, and autoclave/sterilization validations and membrane-based intensified cell culture operation

  • Will be collaborating with cell culture scientists in the operation of fed-batch and perfusion cultures, with responsibilities in characterizing bioreactor set-up and product engineering concepts: scale-up scale-down and process optimizations

  • Direct oversight of process engineering development projects while maintaining an active presence in the lab and collaborating with cell culture operations

  • Execute application-oriented intensified cultures (CFB, Steady-state Perfusion, N-1 perfusion) for new and existing products: Including optimizing bioreactor set-ups, sterilization processes (autoclave and gamma), and clarification method

  • Analyzing and troubleshooting bioreactor processes by monitoring cell growth, viability, protein productivity, and other cell culture metabolites and process parameters. Serve as a process engineering lead

  • Designing experimental investigations, hollow fiber-based processes, analyzing experimental data to effectively present results to the R&D and Product Management teams regularly

  • Proficient in developing protocols and reports for processes in shake flasks and stirred tanks and single-use bioreactors

    Location: Waltham, MA area

    Start Date: ASAP!

    Duration: Direct Hire

    Hours: Mon-Fri; 8am-4:30pm

System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, TPGS, and MOUNTAIN, LTD., are leaders in delivering workforce solutions and integrated services across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible full-time employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.