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Waters Principal Scientist in Milford, Massachusetts

The Scientific Operations group provides globally recognized scientific leadership and knowledge to collaboratively develop differentiated and innovative solutions with our customers, enabling them to solve critical analytical challenges and advance scientific understanding. The area of focus is on biopharmaceutical sciences, specifically on method development for real time characterization of mAbs and cell and gene therapy products.

A Principal Scientist in the Scientific Operations group is responsible for providing expert scientific contributions which impact product development and business outcomes, and positions Waters as a global leader in the analytical instrument market. This will include providing leadership to a team(s) of scientists in the provision of new science, technologies, and practices. The dynamic role of Principal Scientist includes building collaborations across the company and with customers to apply a deep understanding of market needs in the generation of scientific content including publications, patents, and marketing material to support business development. This is a scientific position with an excellent opportunity to grow both professionally and scientifically. The Principal Scientist activities will have a positive impact on the Waters product portfolio, and the overall success of the business.

  • Therapeutic protein characterization using RPLC-MS, SEC, IEX, affinity purifications and automated liquid sample handling.

  • Develop fast LC and LC-MS methods for improved throughput.

  • LC-MS analysis and data interpretation of therapeutic proteins, experiences with Cell and Gene Therapy products are highly desired.

  • Collaborate with internal and external teams to evaluate new technologies and drive innovation

  • Ability to resolve complex problems exercising independent judgment.

  • Review and present work for internal colleagues, external customers, and collaborators

  • Contribute to Product Development team, Marketing team and Strategic team as appropriate

  • Coordinate with Waters Innovation Center at University Delaware for various bioprocessing related projects. Aid and provide quality expertise on experimental design and method optimization. Travel to the Delaware facility is needed.

Core Qualifications

  • PhD degree in Biotechnology, Analytical Chemistry, Cell Biology, Microbiology, Biochemistry, or related discipline with a 3+ years of relevant academic or pharmaceutical industry experience or a Masters/Bachelor’s degree with an 8 + years of relevant industry experience

  • Working knowledge of mass spectrometry and application in biotherapeutic product characterization and manufacturing is highly desirable.

  • Experience with variety of analytical instrumentations such as Liquid Chromatography, CE, cIEF, mass spectrometry and other spectroscopy tools.

  • Ability to interpretate complex data using variety of informatics solutions.

  • Ability to work with limited supervision and function within a collaborative environment

  • Ability to manage multiple projects in parallel, including participation in cross functional project and innovation teams.

Bonus Qualifications

  • Demonstrate strong knowledge of upstream processing fundamentals

  • Good working knowledge and experience with analytical method qualification and validation.

  • Strong background in molecular and cell biology #LI-CB1

Waters Corporation (NYSE: WAT), the world's leading specialty measurement company, has pioneered chromatography, mass spectrometry and thermal analysis innovations serving the life, materials, and food sciences for more than 60 years. With more than 7,000 employees worldwide, Waters operates directly in 35 countries, including 15 manufacturing facilities, with products available in more than 100 countries. Our team focuses on creating business advantages for laboratory-dependent organizations to enable significant advancement in healthcare delivery, environmental management, food safety, and water quality.

Working at Waters enables our employees to unlock the potential of their careers. Our global team is driven by purpose. We strive to be better, learn and improve every day in everything we do. We’re the problem solvers and innovators that aren’t afraid to take risks to transform the world of human health and well-being. We’re all in it together delivering benefit as one to provide the insights needed today in order to solve the challenges of tomorrow.

Diversity and inclusion are fundamental to our core values at Waters Corporation. It is our responsibility to actively implement programs and practices to drive inclusive behavior and increase diversity across the organization. We are united by diversity and thrive on it for the benefit of our employees, our products, our customers and our community. Waters is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, religion, sex, national origin, sexual orientation, age, marital status, disability, gender identity or protected Veteran status.

Bioprocessing , Cell and Gene Therapy, LC-MS, Process Analytical Technology

Company Name: Waters Division

External Company URL:

Street: 34 Maple Street

Telecommute: No

Key Words: Bioprocessing , Cell and Gene Therapy, LC-MS, Process Analytical Technology