Massachusetts Green Jobs

Job title: Senior Data Scientist - Process Modeling

Location: Framingham, MA

About the Job:

The Senior Data Scientist-Process Modeling will be based in the Global CMC Development group in Research & Development (R&D) and will provide process modelling and advanced analytics support for biological process development, with a focus on downstream unit operations.

With a formal training as a process engineer / process systems engineer and a specialization in process modelling, you will have demonstrated skills in the field of mechanistic and hybrid modelling methodologies to support process design, optimization, and process control activities for biopharmaceuticals. You will also have familiarity with machine learning/data-driven modelling methodologies to support these applications.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

Main responsibilities:

• As part of matrix project teams, develop and deploy mechanistic, hybrid and data-driven modelling solutions to support downstream process development activities for a broad range of biopharmaceuticals.

• Use programming languages such as Python, MATLAB, R to translate complex mathematical models into clean and reusable codes for model use and implementation.

• In coordination with the process development group and working closely with the Data Science team, design and analyze targeted experiments required to calibrate and verify model performance.

• Act as a change agent to support the implementation of process modelling in established process development workflows for targeted downstream unit operations.

• Document progress against deliverables with rigorous scientific communication via technical presentations, reports and, when appropriate, scientific publications.

• Track progress against deliverables and maintain a communication plan with key stakeholders and partners across departments.

• For this position, domain knowledge in biologics downstream process development and manufacturing (e.g. affinity/ion exchange chromatography, filtration etc.) is required.

This is an exciting opportunity to demonstrate the benefits of process modelling and data science in a cutting-edge scientific department developing the next generation of Sanofi medicines that will improve the quality of life for patients across the world.

About you:

• Process systems engineer/modeler with a PhD in Chemical/Biochemical Engineering and a minimum of 5 years of industrial experience, or MSc with 9 years of industrial experience.

• Proven track record of developing process models for downstream unit operations for biologics, e.g., affinity/ion exchange chromatography, ultra/ nano / tangential flow filtration etc. for process design, scale-up, scale-down and/or process control purposes.

• Demonstrated ability to translate mathematical models into computer programs using programming languages such as MATLAB, R, Python or similar.

• Domain knowledge in Biology with industrial or academic experience in downstream process development and/or manufacturing.

• Excellent communication skills in an international environment.

• Demonstrated knowledge and application of Machine Learning / Multivariate analysis methodologies to biological processes.

• Knowledge/ experience with process simulation software (e.g. gPROMS, DSPX) and integrated systems modelling applications (i.e. flowsheet modelling).

• Experience in continuous bioprocess manufacture with associated Model Predictive Control (MPC).

• Solid track record of publications in the field of process modelling/process simulation in peer reviewed journals.

Why Choose Us?

• Bring the miracles of science to life alongside a supportive, future-focused team.

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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