Job Information
Sanofi- Genzyme Senior Scientist, Process Chemistry in Cambridge, Massachusetts
In this role you will: Design novel synthetic pathway for drug substances in clinical development. Conduct route scouting in laboratory to demonstrate synthetic viability. Use all imaginable chemistry tools and methods to develop new synthetic pathways (photochemistry, biochemistry, flow chemistry, electrochemistry, on-line analysis, High Throughput Screening, structural analysis (NMR, UPLC/MS). Analyze experimental data to drive synthetic experimental plans. Assist in the design, planning and execution of multi-step experimental studies guided by risk assessment to deliver safe, efficient, robust and scalable drug substance manufacturing processes. Investigate optimization and scale-up of reaction and purification unit operations. Collaborate within project teams by working closely with analytical chemists, process engineers, pilot plant experts and project managers within the CMC Synthetics organization. Communicate scientific results in a clear, concise, and accurate manner via electronic laboratory notebook documentation, development reports, project discussions and presentations. Draft and review technical reports, external publications and patent applications. May include management of outsourced laboratory activities: generating scope of work, supervising activities at CDMOs, validating reports for outsourced activities. About you: Ph.D. in organic or synthetic chemistry. Knowledge in at least one of the following areas: advanced analytics, flow chemistry, high throughput experimentation. Experience in chemocatalysis or biocatalysis including characterization of catalytic processes and/or mechanistic analysis. Computational capabilities and basic coding skills. Strong publication record in peer-reviewed journals. Excellent written and verbal communication skills. Ability to operate with flexibility in a dynamic environment and with tight deadlines. Post-doctoral experience. Proficiency with Microsoft suite. Familiarity with digital tools (e.g. Scifinder-n, and Reaxys) and advanced data analysis software (e.g. Spotfire). Design of experiment, statistical and/or thermo-kinetic modeling. Strategic and innovative thinker with a track record of fresh insightful thinking by developing creative approaches to processes and practices. French language skills Why Choose Us? Bring the miracles of science to life alongside a supportive, future-focused team. Discover endless opportunities to grow your talent and drive your career, whether it?s through a promotion or lateral move, at home or internationally. Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks? gender-neutral parental leave.