Sanofi Group Senior Scientist Deep Data Analytics in Cambridge, Massachusetts
About the Company:
Sanofi is a global life sciences company committed to improving access to healthcare and supporting the people we serve throughout the continuum of care. From prevention to treatment, Sanofi transforms scientific innovation into healthcare solutions, in human vaccines, rare diseases, multiple sclerosis, oncology, immunology, infectious diseases, diabetes and cardiovascular solutions and consumer healthcare. More than 110,000 people in over 100 countries at Sanofi are dedicated to make a difference on patients’ daily life, wherever they live and enable them to enjoy a healthier life. As a company with a global vision of drug development and a highly-regarded corporate culture, Sanofi is recognized as one of the best pharmaceutical companies in the world and is pioneering the application of Artificial Intelligence (AI) in the R&D organization including drug discovery, chemical manufacturing and control, translational research, clinical development, and regulatory document management and submission. Details of the organization and the company’s mission and goals can be found on our website (http://www.sanofi.us/l/us/en/index.jsp).
Data Analytics and Artificial Intelligence (AI) methods can speed up drug discovery, cut R&D costs, decrease failure rates in drug trials and eventually create better medicines, to improve the lives of our patients. There is a wide range of applications along the pharma R&D value chain, including
Identification of new pathways and targets using “-omics” analysis, identification of novel therapeutic targets & biomarkers, personalized medicine based on “-omics” markers, discovery of connections between drugs and disease phenotypes
Development of new therapeutics, through property prediction, novel drug combinations, drug repositioning and analysis of protein features and characteristics
Increasing efficiency and reducing manual work, through analysis of biomedical & process information as well as clinical trial and patient-related data, natural language processing & automated document generation
Improving outcomes and probability of success (PoS), through aggregation and analysis of relevant data, forming and qualifying hypotheses, assessing risk, designing and optimizing clinical trial scenarios, and enabling better decision-making overall
We are looking for a senior scientist in Deep Data Analytics, to become a member of a newly formed global team from various data science disciplines. He/she will be reporting into the global Head of Deep Data Analytics. The global team of Deep Data Analytics is part of a new Digital Data & Sciences platform within Sanofi R&D
The responsibilities of the Senior Scientist in Deep Data Analytics will include:
Apply artificial intelligence and machine learning approaches (e.g. classification, clustering, artificial neural networks, deep learning) on clinical data sets (biomarker profiles, genome-wide datasets, medical imaging data, continuous data from wearable devices)
Support patient classification by generating hypothesis for biomarkers to identify treatment responders, align with biostatisticians for hypothesis validation
Update and report relevant results to interdisciplinary project teams and stakeholders
Develop and maintain strong working relationship with other modeling groups within TI organization, as well as with biostatisticians outside of the TI organization.
Maintain a keen awareness of developments in data technologies, analytics, methods and systems especially for AI&ML approaches for the analysis of clinical data, special interest for analysis on data from wearable devices and imaging data
Evaluate and coordinate academic collaborations and outsourcing partners (CROs) in area of application of AI&ML for clinical data analysis, in particular for analysis of data from wearable devices and imaging data
Qualifications & Requirements:
An MS or PhD in a field related to Data Analytics, AI or Machine Learning such as: Computer Science, Mathematics, Statistics or Physics
3+ years experience in in the pharmaceutical industry with a strong record of accomplishments and experience in evaluation, development and application of AI&ML approaches
Familiarity with Deep Learning techniques, various network architectures (CNNs, GANs, RNNs, Auto-Encoders, etc.), regularization, embeddings, loss-functions, optimization strategies, or reinforcement learning techniques such as REINFORCE, DQN, PPO, etc.
Familiarity with one or more typical deep learning or reinforcement learning frameworks: TensorFlow, Keras, Caffe, MxNet, TORCH, OpenAI Gym, Keras-RL etc.
Good knowledge of R, Python and MATLAB
Knowledge of Extract, Transform and Load (ETL) frameworks
Knowledge of Enterprise Data Warehouse (EDW) and data management systems
Specific knowledge & experience in one or more of the following would be a plus: image analysis, natural language processing, automated document generation, reinforcement learning, control theory, knowledge representation (semantic models, graph databases, etc.), distributed systems and high-performance computing methods.
Demonstrated leadership experience and demeanor to spearhead implementation of novel data science-related methods
Preferred Qualifications & Requirements:
A change agent with a combination of business, science & technology, and diplomatic skills
Strong methodological capabilities and broad experience across different stages of the pharma R&D process
Experience with SQL and NoSQL databases
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.
Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions.
With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe.
Sanofi, Empowering Life
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