Sanofi Group Scientist Translational Disease Modeling, Digital Data Science in Cambridge, Massachusetts
The Translational Disease Modeling (TDM) group at Sanofi is seeking to hire a highly talented modeling scientist to support its portfolio in R&D. The TDM group is part of Data & Data Science department of Sanofi. This position is for a modeling scientist, with emphasis on disease progression modeling and population PKPD modeling. The primary focus will be on modeling efforts which quantitatively integrate drug exposure and response with longitudinal disease time course incorporating biomarkers of disease severity and/or clinical outcomes. The position will be based in Bridgewater, NJ or Cambridge, MA.
- Design, and perform pharmacometric analyses of drug disease progression using a variety of tools and approaches (e.g., mechanistic population PKPD modeling approaches) in collaboration with internal and external partners.
Develop, and implement population PKPD and disease progression modeling and simulation approaches.
Communicate key modeling findings to internal and external audiences.
Acquire in-depth understanding of biology relevant to modeling efforts.
Maintain state-of-the art knowledge of relevant modeling approaches and techniques.
PhD, or PharmD in Pharmaceutical Sciences, Pharmacology, Statistics, Applied Mathematics, or related field with track record of productivity in the areas of statistics, pharmacometrics, population PK/PKPD, disease progression modeling, or related area, as manifested by publications and scientific presentations.
OR a M.S. Degree with at least 4 years of relevant experience in the areas of clinical pharmacology, modeling/simulation, statistics, OR other related areas as manifested by publications and scientific presentations.
Applied working knowledge of non-linear mixed effect modeling is required along with knowledge of Nonlinear Mixed effect modeling software packages.
Solid understanding of statistics and quantitative pharmacology principles.
Excellent communication skills (both verbal and written) of technical and non-technical information.
Effective collaborative spirit to function in a highly-matrixed organization.
Knowledge And Skills Desirable But Not Essential:
Experience in rare diseases or neurology.
Bayesian statistical modeling.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.
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