Sage Therapeutics Scientist / Senior Scientist, Toxicology in Cambridge, Massachusetts

Overview

General Scope and Summary

SAGE Therapeutics is searching for a creative, resourceful, integrative thinker for an important role that is responsible for the design and oversight of the nonclinical safety testing programs for assigned clinical candidates in development.

Roles and Responsibilities

  • Responsible for nonclinical study design, contract research laboratory (CRO) study director interactions/monitoring, study result interpretation, report finalization, and supporting preparation of integrated nonclinical summaries for IND

  • Design safety testing program (including safety pharmacology and toxicology testing) for early discovery and assigned clinical candidates.

  • Review and finalize study reports as per GLP’s.

  • Serve on selected project teams and/or sub teams.

  • Assess mechanism(s) of toxicity to determine clinical relevance and ways to minimize clinical impact.

  • Collaborate with Discovery Research in the screening and selection of final IND candidates.

  • Work cross-functionally across the organization, including Regulatory, Research, Medical Science/Safety, Quality Assurance and CMC groups.

Experience, Education and Specialized Knowledge and Skills

  • Successful candidates will have a MS with 5-10 years or Ph.D. with 1-3 years of experience as a toxicologist within the biopharmaceutical industry.

  • Candidates must be familiar with IND testing programs and the worldwide nonclinical testing guidelines to support clinical development and registrational filings.

  • Knowledge of pharmacokinetics or toxicology specialization is desirable.

  • This role requires approximately 20% travel.

  • Embrace our core values: Put People First, Do Big, Be Accountable, Grow through Learning and Change, and Work Fun.

  • Excitement about the vision and mission of Sage.

ID 2017-1520

# of Openings 1

Category Research & Development

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