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Novartis Pharmaceuticals Principal Scientist, High Throughput Biology Profiling in Cambridge, Massachusetts


Job ID:


Job Description:

400+ scientists globally. That is your opportunity for partnerships within Chemical Biology & Therapeutics (CBT) to innovate the science of drug hunting.

What would you do with the state of the art systems and technology combined with automation to solve the toughest biology problems at scale? The High Throughput Biology (HTB) team is looking for a creative, motivated scientist with practical experience in developing and executing assays taking advantage of all that NIBR has to offer. We are looking for someone to elevate our endeavors in phenotypic screening in the discovery process.

HTB is part of the larger Chemical Biology and Therapeutics (CBT) department that encompasses the full-spectrum of sophisticated capabilities needed to succeed in a state-of-the-art drug discovery biopharma laboratory. This position will collaborate closely with research teams within CBT, as well as across diverse Disease Areas.

Your responsibilities Include:

  • collaborating closely with colleagues to assist in the development and implementation of disease relevant and biochemical assays on automated systems.

  • developing, optimizing, adapting, and evaluating assay protocols suitable for automated screening and HTS using compounds or genetic reagents

  • working with automation team members and collaborating with reagent production laboratories, detail the large amount of data generated in your studies in databases and present your results in project team meeting

  • Make connections and propose hypotheses from the multitude of data at your disposal.

  • Assess and implement emerging cutting-edge technologies and novel assays

  • Engage with multidisciplinary project teams to design, execute, and interpret experiments

  • Develop productive relationships with collaborators and represent Novartis values of integrity, courage, innovation, performance, quality, and collaboration

  • Leading projects from the bench and contributing to the growth and development of associates in the group


Position Title:

Principal Scientist, High Throughput Biology Profiling

Minimum requirements:

What You'll Bring to the Role:

  • Ph.D. and 3+ years of experience, or a BS/MS with an extensive background in HTS, and experience leading a team.

  • Proven track record of assay development in an academic or industrial environment

  • Experience in or the aptitude to learn large-scale data handling and databases

  • Experience with processing and interpreting profiling data.

  • Experience in laboratory automation and interest in novel readout technologies with experience in High-Throughput Screening an advantage

  • Open and proactive communicator, excellent writing skills, customer focused to interact with various partners in a multidisciplinary team setting

  • Reliable and flexible teammate, used to sharing tasks and projects

  • Prioritizing, keeping timelines and good organization skills

  • Independent and accurate working style, results-driven and committed to quality

Desirable Requirements:

  • Strong background in biochemistry and/or cell biology to understand mechanism of disease

  • Have understanding of or ability to learn basic computer programming concepts and languages

Why consider Novartis?

799 million. That’s how many lives our products touched in 2019. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people’s lives?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

Imagine what you could do at Novartis!

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Commitment to Diversity & Inclusion:

Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration, and empowers our people to unleash their full potential.

Job Type:

Full Time



Work Location:

Cambridge, MA

Functional Area:

Research & Development



Business Unit:


Employment Type:


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EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

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