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Novartis Pharmaceuticals Principal Scientist - ADME, DDI in Cambridge, Massachusetts


Job ID:


Job Description:

1 ADME Scientist is all it takes to advance new therapies to improve patients’ lives. At the Novartis Institutes for Biomedical Research (NIBR), we are reimagining medicine using science-based innovation.

At the Novartis Institutes for Biomedical Research (NIBR) we are reimagining medicine using science-based innovation. The ADME In-Vitro team is looking for a Scientist with a mixed role of coordinating laboratory work and project representation of the discipline.

What you’ll be doing:

In this role you will actively participate in multi-disciplinary project teams by providing ADME expert input and guidance for DDI-related questions encountered during the drug discovery and development stages.

You will assist in developing new in-vitro assays/models for enzyme/transporter inhibition and phenotyping with improved predictive power. Adapt the assay portfolio to the evolving needs of the organization and schedule/monitor studies performed at CROs.

You will also develop a compilation of technical documents, study reports, and documents in support of regulatory submissions.


Position Title:

Principal Scientist - ADME, DDI

Minimum requirements:

Minimum requirements :

What you will bring to the role:

Ph.D. degree in Pharmaceutical Sciences, Pharmacology, Toxicology, Biochemistry, Biology, Chemistry, Bioengineering or equivalent

5 plus years of experience in ADME, particularly in the translational aspects.

An understanding of drug metabolism, drug transport, drug-drug interactions, and pharmacokinetics principles.

Working knowledge of general laboratory techniques used in the ADME in-vitro field including LCMS and handling radioactivity.

Experience conducting and coordinating studies at CROs is desirable.

You will work independently, be capable of providing expert technical/scientific assistance on projects and provide assistance with health authority interactions. Good oral and written communication skills are essential.

Why consider Novartis?

Transformative medicines need transformative thinking. We believe the answers are found when curious, courageous, and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data.

Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to seek the world’s toughest medical challenges.

We are Novartis. Join us and help us reimagine medicine.

Job Type:

Full Time



Work Location:

Cambridge, MA

Functional Area:

Research & Development



Business Unit:

Translational Medicine

Employment Type:


Company/Legal Entity:


EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.

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