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Editas Medicine Associate Scientist II, Process and Analytical Development: Gene Therapy - 2146 in Cambridge, Massachusetts

What if you could repair broken genes? That is the question we ask ourselves at Editas Medicine. We’re focused on translating the power and potential of the CRISPR/Cas9 and CRISPR/Cpf1 (also known as Cas12a) genome editing systems into a robust pipeline of medicines for people living with serious diseases around the world. Our goal is to discover, develop, manufacture, and commercialize transformative, durable, precision genomic medicines for many diseases. We’re looking for talented, dedicated, passionate people to join our team and help us pioneer this field and do big, bold things that have never been achieved before. Are you full of hope, possibilities, and a belief that, working together, we can truly revolutionize the development of medicines to help patients around the world? If the answer is yes, then Editas Medicine is the place for you.

This role in Operations contributes to Editas efforts to develop safe and effective cellular therapies using CRISPR-based gene editing technologies. This role is located within Protein and RNP Process Development and the core competencies we are looking for are of an individual who has experience running cellular, molecular, and/or biophysical assays. These will be used to support process development activities. The ideal candidate doesn’t need to have experience in all three assay types but have the ability to and desire to quickly learn all three types of assays.

Key Responsibilities & Accountabilities:

  • Work collaboratively with Analytical Development to learn the most updated cellular, molecular, and biophysical methods in order to perform testing to support Protein and RNP Process Development.

  • Independently or collaboratively perform Protein and RNP process development experiments to support multiple programs.

  • Document all experimental work, supporting information, and data in an electronic lab notebook (eLN) in a timely manner.

  • Compile and present data to program teams.

  • Cross-train personnel on assays, as required, and provide guidance to junior research associates.

  • Author and review batch records, technical reports, and supporting procedures.

Requirements

Knowledge, Skills & Capabilities:

  • Experience with cell culture and aseptic technique is required.

  • Experience running biomolecular assays such as ddPCR, RT-PCR, and ELISA are highly preferred.

  • Experience running biophysical assays and working with common systems such as HPLCs and UPLCs is preferred.

  • Protein Process development experience is not required, but highly preferred.

  • Strong verbal and written communication skills.

  • Strong organizational skills with the ability to multi-task, problem-solve, prioritize assignments, and adjust priorities to meet goals in a fast-paced environment required. 

  • Ability and desire to learn cutting edge analytical and process techniques quickly.

  • Attention to detail and the ability to work individually, within a multi-disciplinary team in a matrix environment, as well as with external partners and vendors.

  • Strong leadership skills.

Education & Relevant Work Experience:

  • BS degree in life sciences with 8+ years of related industry experience or MS degree in life sciences with 6+ years in a discipline such as Biological Sciences, Biotechnology, Pharmaceutical Sciences, or Biomedical Engineering.
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