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Alexion Pharmaceuticals Senior Manager, Development & Safety Operations in Boston, Massachusetts

Some opportunities happen only once in a lifetime - like a job where you have the chance to change lives. At Alexion, people living with rare and devastating diseases are our Guiding Star. We are driven to continuously innovate and create meaningful value in all we do to help patients and families fully live their best lives. We value the uniqueness and diversity of our employees and recognize that nurturing the diverse perspectives and strengths of our people translates into innovative breakthroughs for patients.

This is what you will do:

This position will serve as the financial and resource expert for the Development and Safety function. Partners internally with various functions to develop an annual operating plan/budget and resource forecasting/management across Development & Safety. Develops robust processes and systems for business operations and drives compliance with these processes. This role also drives the oversees finalization of contracts, accrual reporting, tracking, invoicing, and financial reconciliation in partnership with Finance, business owners and external vendors.

You will be responsible for:

  • Partern with functional leaders, Finance and portfolio management to deliver key Development & Safety Business Operations Activities:

  • Resource Planning

  • Financial Forecasting & Accruals,

  • Contracting,

  • Resource Management : Partners with Development & Safety leadership to build efficient resourcing plans for optimal utilization of internal and FSP resources. Develops capacity and resource reporting and analytics to help leaders manage changing portfolio demand

  • Budget Management : Manages Development & Safety’s functional budget and serves as primary representative to key stakeholders within Alexion. Responsible for monthly Development & Safety accruals and forecasts.

  • Contract Management : Develops robust processes to manage POs and invoice approvals, responsible for timely reconciliations, and partners with Finance and Procurement to ensure overall compliance.

  • Process Management : Accountable for implementing highly effective processes and efficient systems to manage functional budgets and resource management.

  • Compliance : Ensure compliance to appropriate budget management SOPs. Develop oversight and governance processes to ensure compliance.

    You will need to have:

  • Bachelor’s Degree required

  • 5+ years of development or project management experience within the biopharma industry

  • Proven experience in budget and resource forecasting and management processes, methodologies and systems.

  • Proven experience in strategic planning processes at the functional and organizational level

  • Strong skills in leading and managing cross-functional projects with significant business impact.

  • Proven excellence in operational strategy and demonstrated ability to execute operationally

  • Advanced ability to work in a matrix environment and develop constructive partnerships with internal and external stakeholders.

  • Exceptional written and oral communication skills

  • Be a trusted partner in the functional leadership team and accordingly may be involved in the preparation of functional goals.

  • The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.



    Alexion is a global biopharmaceutical company focused on serving patients and families affected by rare diseases and devastating conditions through the discovery, development and commercialization of life-changing medicines. Headquartered in Boston, Massachusetts, Alexion has offices around the globe and serves patients in more than 50 countries. Further information about Alexion can be found at: .

    Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion has taken critical steps to protect colleagues, loved ones, and patients from COVID-19 and its variants. All US-based employees must comply with Alexion's COVID-19 vaccination mandate. Alexion provides exceptions based on applicable state law as well as reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding a legally required exemption or accommodation, please contact Alexion participates in E-Verify.

    As a leading employer in our industry, Alexion offers a highly competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, and much more.

    AstraZeneca completed its acquisition of Alexion, marking the creation of Alexion, AstraZeneca Rare Disease. If you're interested in career opportunities with AstraZeneca, click here ( .