Beth Israel Deaconess Medical Center Research Associate in Boston, Massachusetts
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Department Description:The Friedman and Pollak laboratories study inherited kidney disease using human genetics, transgenic mouse models, and molecular biology. We use cutting edge techniques such as CRISPR-transgenic mice, single-cell RNA sequencing, and super-resolution microscopy to understand how genetic variants in the APOL1 gene cause kidney disease in African Americans. Our research environment is highly collaborative and includes projects and meetings with a wide range of other research groups, providing exposure to new ideas and opportunities to learn new techniques.
Job Location:Boston, MA
Job Summary:Exciting opportunity to work on an academic/pharma drug discovery collaboration to treat kidney disease. Conduct and help coordinate a wide range of routine and specialized laboratory tests using molecular, cell biology and/or biochemistry techniques, and animal models. The successful applicant will have previously demonstrated a high degree of independence in conducting research projects and may have technical expertise in specific area(s) that surpasses basic performance expectations. Understanding the theory behind tests and procedures, performing lab procedures with speed and precision, and a high degree of reliability are key attributes needed for this position. Work is performed in a multi-disciplinary, fast-paced laboratory and requires excellent problem-solving abilities plus the ability to multi-task. Experience with transgenic murine models preferred.
This position involves working on a research team under the direction of the Project Manager.
Assisting in the management and development of a large transgenic mouse colony, which may include overseeing research assistants, experimental planning, and generation of new transgenic lines.
Designing, performing, and interpreting non-hypothesis based experiments using mouse and human samples. Techniques may include single-cell RNA sequencing, proteomics, and metabolomics.
Conducting hypothesis based experiments using pharmacology and genetic manipulation in transgenic mice. Will assist in interpreting results and designing/performing follow up experiments.
Bachelor's degree in Life Sciences or related field required. Master's degree preferred.
3-5 years related work experience required.
Bachelor's degree and four years experience. Or, a Master's degree and two years experience.
Advanced skills with Microsoft applications which may include Outlook, Word, Excel, PowerPoint or Access and other web-based applications. May produce complex documents, perform analysis and maintain databases.
Decision Making:Ability to make decisions that are guided by general instructions and practices requiring some interpretation. May make recommendations for solving problems of moderate complexity and importance.
Problem Solving:Ability to address problems that are varied, requiring analysis or interpretation of the situation using direct observation, knowledge and skills based on general precedents.
Independence of Action:Ability to follow precedents and procedures. May set priorities and organize work within general guidelines. Seeks assistance when confronted with difficult and/or unpredictable situations. Work progress is monitored by supervisor/manager.
Written Communications:Ability to communicate clearly and effectively in written English with internal and external customers.
Oral Communications:Ability to comprehend and converse in English to communicate effectively with medical center staff, patients, families and external customers.
Knowledge:Ability to demonstrate full working knowledge of standard concepts, practices, procedures and policies with the ability to use them in varied situations.
Team Work:Ability to work collaboratively in small teams to improve the operations of immediate work group by offering ideas, identifying issues, and respecting team members.
Customer Service:Ability to provide a high level of customer service to patients, visitors, staff and external customers in a professional, service-oriented, respectful manner using skills in active listening and problem solving. Ability to remain calm in stressful situations.
Physical Nature of the Job:
Medium work: Exerting up to 50 pounds of force occasionally and or up to 20 pounds of force frequently. Job is physical in nature and employee needs to stand and/or move around through the majority of their shift.