Merck Principal Scientist, In Vivo Pharmacology in Boston, Massachusetts

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its legacy for over a century. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases.

We are seeking a highly motivated and experienced Principal Scientist with a strong background within In Vivo Pharmacology - Oncology / Immuno-oncology to join the Department of Pharmacology at Merck Research Laboratories - Boston. The successful candidate is expected to drive scientific excellence by establishing best practices in the development and implementation of Oncology Model Development, In Vivo efficacy, PK / PD, and non - GLP tolerability studies while serving as a key intellectual contributor in the conception and implementation of new projects. The role will involve significant interaction and collaboration within the company and with external partners and will require the ability to maintain positive collaborations of this nature. The selected candidate will report to the Director of In Vivo Pharmacology - Oncology, MRL - Boston and would be expected to work at the bench when needed.

The successful candidate will have a track record of innovative and collaborative research as demonstrated through peer - reviewed publications in oncology and / or cancer immunotherapy. They will perform experiments using preclinical species to support the discovery of novel compounds for the treatment of cancer and to expand on capabilities that will further the clinical development and success of Keytruda, Lynparza, and Lenvima. Experience in managing external studies at CROs and academic collaborators including monitoring study execution and ensuring finalization of study reports within set timelines is a plus. An ability to communicate clearly and collaborate effectively with colleagues in the pharmacology department as well as scientists from different disciplines and different sites is essential.

EDUCATION:

  • Ph.D with a minimum of 8 years of experience in oncology drug discovery.

REQUIRED SKILLS:

  • Experience using preclinical models to evaluate the pharmacology of novel cancer drugs

  • A minimum of 8 years of oncology drug discover experience - can be a combination of post - doctoral and industry experience.

  • Candidate should be a strong team player with excellent oral and written communication skills and with a demonstrated ability to work independently to design experiments, interpret data, troubleshoot, and suggest next steps.

  • Proven skills in leading scientific teams

PREFERRED SKILLS:

  • Experience with syngeneic tumor models and genetically engineered mouse models of cancer to support the development of novel tumor immunotherapy programs.

  • Experience managing external projects, including study design, data and sample management.

  • Experience in Cell Biology, Cell Biochemistry, and Molecular Biology focused on oncology or tumor immunology.

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life.

If you need assistance and/or a reasonable accommodation due to a disability during the application or the recruiting process, please send a request to staffingaadar@merck.com .

Search Firm Representatives Please Read Carefully:

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Merck is an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations.

Job Pharmacology - DPS

Merck is an equal opportunity employer, Minority/Female/Disability/Veteran – proudly embracing diversity in all of its manifestations.

Title: Principal Scientist, In Vivo Pharmacology

Primary Location: NA-US-MA-Boston

Requisition ID: PHA001458