Alexion Pharmaceuticals Medical Director, Nephrology in Boston, Massachusetts
The Medical Affairs Director Nephrology will provide support for strategic planning and leadership in our nephrology program in the US. Responsible for providing strong scientific and medical support with an in-depth understanding of the Nephrology medical landscape. Support the development and implementation of the short and long-term strategy, practices and infrastructure within the US aligning with overall Alexion medical affairs strategy and effective cross-functional collaboration. Support the Alexion Global Medical Affairs mission to maximize patient outcomes by setting and continuously advancing the evidence-based medical standard of care.
Job Duties & Responsibilities
Develop and implement US strategy and plan for US MA activities for the Nephrology by providing medical leadership, insight and strategy to the US Nephrology medical affairs team across various internal functions. Responsible for the following:
Lead on the situational assessment and the US product strategy development including harmonization of activities involving KOLs.
Develop in-year medical strategy and tactical plan for the US Medical Affairs team working closely with the TA Lead.
Implementation and budget plan for US Medical Team initiatives.
Provide medical strategic recommendation for in-line life cycle management (LCM) and late phase pipeline programs.
Lead evidence generation projects
Support registration program working closely with GMA and geographically expansion strategy
Support Phase 3b/4 and ISR evidence generation strategy for late phase pipeline and in-line TA programs.
Support clinical study design (non-registration phase IIIb/IV, registries, outcomes research etc.) for late phase pipeline and in-line Nephrology programs in close collaboration with relevant functions.
Provide medical review and ensure alignment with Nephrology strategy of Investigator sponsored research (ISR) proposals.
Provide clear strategic guidance to scientific communication, internal medical training, external medical education (CME, Symposia, medical education), Medical info, PEVT teams in developing functional plans supporting US medical strategy
Contribute medical perspective to commercial strategy as appropriate
Support TA lead with team’s performance in terms of goals and delivery of US medical plans
Serves as the medical expert and resource within ALXN in support of the therapeutic area.
Lead content development and presentation for external medical education programs and other Medical initiatives.
Develop, conduct, or participate in therapeutic training programs for Alexion personnel.
Medical affairs review of congress executive summary report.
Establishes strategic partnerships with centers of excellence and KOLs in areas of scientific interest and serves as conduit for flow of information both out to the medical community and into the company.
Working closely with the TA lead and Field Medical leadership in the development and execution of US KOL medical engagement strategy
Establish and/or enhance partnerships with key academic institutions and develop relationships with key thought leaders
Planning, designing and managing medical Advisory Boards and gather insight from regional/local medical Advisory Boards
• Must have a MD, PhD or Pharm D level degree or equivalent
• Experience leading Medical Affairs function
• Proficient in Medical Governance, with extensive regulatory and compliance experience leading a Medical Affairs organization
• Excellent communication skills both written and verbal.
• Ability to lead and motivate a team, both internally and remotely
• Excellent interpersonal skills with demonstrated track record and ability to drive results as an effective a team member and project leader
• Previous Clinical Operations experience (design and implementation of clinical trials)
• Proven ability to manage budget and resources
• Strong business acumen
• Ability to build partnership access between HQ and affiliates
• Flexibility and ability to adapt to changing conditions
• Excellent problem solving, organizational, and negotiating skills
• Must demonstrate an energy and enthusiasm which brings a positive approach to all challenges
• Sense of ethics and responsibility
• Travel required up to 40%
Scientific and technical acumen in Nephrology/Hematology and rare diseases
Health Outcomes Research/Reimbursement Experience
Experience with management and leadership acquired in a multicultural environment involving diverse and remote teams is a plus
Some opportunities happen only once in a lifetime - like a job where you have the extraordinary opportunity to change lives. At Alexion, such opportunities arise through our unwavering mission to serve patients and families affected by rare diseases. These patients are our guiding star, and we act with integrity, urgency, and discipline because we know their lives are at stake.
Alexion is a global biopharmaceutical company focused on serving patients and families affected by rare diseases and devastating conditions through the discovery, development and commercialization of life-changing medicines. As a leader in rare diseases for more than 25 years, Alexion has developed and commercializes two approved complement inhibitors to treat patients with paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS), as well as the first and only approved complement inhibitor to treat anti-acetylcholine receptor (AchR) antibody-positive generalized myasthenia gravis (gMG) and neuromyelitis optica spectrum disorder (NMOSD). Alexion also has two highly innovative enzyme replacement therapies for patients with life-threatening and ultra-rare metabolic disorders, hypophosphatasia (HPP) and lysosomal acid lipase deficiency (LAL-D) as well as the first and only approved Factor Xa inhibitor reversal agent. In addition, the company is developing several mid-to-late-stage therapies, including a copper-binding agent for Wilson disease, an anti-neonatal Fc receptor (FcRn) antibody for rare Immunoglobulin G (IgG)-mediated diseases and an oral Factor D inhibitor as well as several early-stage therapies, including one for light chain (AL) amyloidosis, a second oral Factor D inhibitor and a third complement inhibitor. Alexion focuses its research efforts on novel molecules and targets in the complement cascade and its development efforts on the core therapeutic areas of hematology, nephrology, neurology, metabolic disorders and cardiology. Headquartered in Boston, Massachusetts, Alexion has offices around the globe and serves patients in more than 50 countries. Further information about Alexion can be found at: www.alexion.com.
As a leading employer in our industry, Alexion is proud to offer a highly competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more.