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Rhythm Pharmaceuticals Director, Program Management in Boston, Massachusetts

Company Overview

Rhythm is a biopharmaceutical company aimed at developing and commercializing therapies for the treatment of rare genetic diseases of obesity. Working at Rhythm means that you are part of a team that’s passionate about transforming the lives of people living with rare genetic diseases of obesity. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together.

Job Summary

The Director, Program Management will lead Program Management across the global organization. They will drive the development, execution, and tracking of integrated project plans and cross-functional team for Rhythm assets. The scope will include research, development, and commercial stage projects/programs. As Rhythm continues to grow, the incumbent may have direct reports to manage and develop into skilled program/project managers. The role reports into the CTO.

Rhythm values the face-to-face interactions we have while in the office and currently operates in a hybrid work model for Boston-based roles.

Responsibilities and Duties

  • Lead the definition of program team plans including evaluating, optimizing, and planning of alternative development plans and associated operational scenarios

  • Lead development of program critical path, decision criteria and milestones/decision gates

  • Prioritize deliverables and align across functions

  • Develop/ensure accuracy of program team timelines, align with each line function’s plan

  • Leadership to establish annual team goals in alignment with Corporate Goals

  • Drive process and accountabilities for creation of key cross functional deliverables

  • Track and drive program deliverables across all functions

  • Ensure that potential budget, timeline and strategy variances are proactively brought forth from functions; assess options for tradeoffs within overall budget, timeline, and strategy

  • Lead team to prepare and implement cross functional program risk management plans including, risk and opportunity identification and assessment, mitigation strategies and contingency planning

  • Propose plans/strategies that result in de-risking the overall program

  • Ensure alternative development options are thoroughly evaluated, including pros, cons, and risks

  • Lead operational aspects of program team: chartering, agendas, driving and documentation of actions and decisions, meeting facilitation, timelines, overviews, etc.

  • Lead cross functional teams; lead cross functional interactions between global and functional teams

  • Manage and archive project and program information

  • Conduct and implement key lessons learned and after-action reviews as appropriate to the program/team

  • Drive program teams towards the delivery of project milestones on time, budget, and within scope through utilization of project management tools.

  • Create a culture of high performing teams with clear accountabilities, robust scientific debate, and respectful interactions that foster trust.

    Qualifications and Skills:

  • Bachelor’s degree in scientific area and/or business or financial management preferred, advanced degree preferred

  • Pharma/biotech experience with demonstrated success in leading programs with proven results and effective leadership and management skills

  • 10+ years of related education and role specific experience

  • Demonstrated program management expertise and experience; project management certification preferred

  • Demonstrated success in leading through influence

  • Demonstrated ability to integrate information and apply creative thinking and proactive problem-solving skills

  • Demonstrated ability to identify, build, and implement solutions to cross functional team issues

  • Excellent balanced approach to process versus results-driven leadership and management skills

  • Excellent negotiating skills; influencing skills up, down and across the organization

  • Scientifically adept, great communication skills, knowledge of drug development, strategic, organized, and experience with project management tools

    This role is based out of our Corporate office in Boston, Massachusetts. Rhythm’s operates in a hybrid-work model. Candidates applying must be willing and able to be in the Boston office in coordination with their department and business needs.

More about Rhythm

Rhythm is a biopharmaceutical company aimed at developing and commercializing therapies for the treatment of rare genetic disorders of obesity. The company is targeting the melanocortin-4 receptor (MC4R) pathway that is impaired due to genetic variants. This is a key biological pathway that regulates weight and hunger. A central element of Rhythm’s mission is to improve the understanding of these disorders and develop management strategies for patients who have no treatment options available to them. Rhythm was founded in 2008 and is based in Boston, MA. The company’s clinical development program is currently focused on several rare genetic disorders of obesity, all driven by genetic variants in the MC4R pathway. For healthcare professionals, please visit for more information. For those who may be affected or would like to learn more, visit for more information.

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