Alexion Pharmaceuticals Director, Global Health Economics and Outcomes Research (GHEOR) in Boston, Massachusetts

Position Summary

The Director, Global Health Economics and Outcomes Research (GHEOR) leads the strategic development and execution of health economics and outcomes research strategies to support the worldwide launch and reimbursement of products across a range of disease areas. Through key leadership and partnership across cross-functional teams, the job holder embeds global HEOR strategy into broader disease area and clinical development strategies. This collaboration builds strategies to demonstrate and differentiate the value proposition and corresponding scientific evidence of Alexion products for payers, patients, clinical institutions and other key influencers. The Director, Global HEOR partners with and provides thought leadership to Market Access, Clinical Development and Commercial teams as well as regions and countries.

Job Duties & Responsibilities

Utilizes in-depth knowledge of disease area and portfolio strategy in combination with health economics and outcomes research to develop and execute the Global HEOR strategy. Ensures payer relevant endpoints and evidence generation strategies are implemented throughout the product lifecycle. Accountable for the following:

  • Builds collaborative relationships with cross-functional leaders across Research & Development, Commercial, Market Access organizations to maximize evidence generation efforts to optimize launch and sustained reimbursement throughout the product lifecycle

  • Partners with the Therapeutic Area (TA) heads to develop TA business strategies and clinical development plans that will provide a competitive advantage to differentiated payer evidence; drives efficient and innovative HEOR study development and study execution and dissemination.

  • Continually monitors the global marketplace for market access issues, identifies access/demand hurdles and creates plans to demonstrate the value and differentiation of assets within the therapeutic area portfolio

Ensures Alexion maintains external credibility and relationships to validate research findings and communications. Accountable for the following:

  • Cultivates and maintains relationships with key experts, influencers, and customer segments to foster and maintain Alexion’s credibility to support the value and reimbursement of Alexion products

  • Delivers presentations on behalf of Alexion at various industry and scientific forums and/or contribute to publications

  • Maintains the relationship with external agencies and monitors their performance to ensure that performance and deliverables meet business expectations

Contributes to the global HEOR infrastructure to provide direction and guidance to Regional HEOR teams. Accountable for the following:

  • Develops best practices in HEOR including approaches to areas including research methodologies, study designs, endpoints that provide scientifically sound protocols, policies, tools and outcome impact.

  • Provides global oversight and guidance to country teams to adapt the global strategies into tactical plans through robust Health Technology Assessment processes to achieve optimal access and sustained reimbursement throughout the product lifecycle

  • Identify areas for process improvements, economies of scale, and other quality and efficiency measures

Essential Qualifications

  • PhD or equivalent combination of education and experience

  • 5+ years prior experience in HEOR or Market Access in the biopharmaceutical/pharmaceutical industry

  • Thorough understanding of the field of Health Technology Assessment at a global level and experience of successful negotiations through the HTA processes

  • Understanding of the global market access landscape and the US health care environment

  • Knowledge of the drug development and commercialization process

  • Recognized as a strong leader with a proven track record of effectively managing, influencing and developing people including those who are not direct reports: demonstrated ability to lead and deliver results in a matrix environment, and solve complex issues that cross multiple stakeholders

  • Excellent interpersonal skills with a track record of effectiveness as a team player; excellent oral/written communication and presentation skills

  • Excellent project leader who can effectively manage multiple competing priorities to completion

  • Global mindset and ability to work with multicultural teams

  • Flexibility and adaptability to internal and external change

Preferred Qualifications

Experience and knowledge in rare disease conditions

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Some opportunities happen only once in a lifetime - like a job where you have the extraordinary opportunity to change lives. At Alexion, such opportunities arise through our unwavering mission to serve patients and families affected by rare diseases. These patients are our guiding star, and we act with integrity, urgency, and discipline because we know their lives are at stake.

Alexion is a global biopharmaceutical company focused on serving patients and families affected by rare diseases through the discovery, development and commercialization of life-changing therapies. As the global leader in complement biology and inhibition for more than 20 years, Alexion has developed and commercializes the first and only approved complement inhibitor to treat patients with paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and anti-acetylcholine receptor (AchR) antibody-positive generalized myasthenia gravis (gMG). Alexion also has two highly innovative enzyme replacement therapies for patients with life-threatening and ultra-rare metabolic disorders, hypophosphatasia (HPP) and lysosomal acid lipase deficiency (LAL-D). In addition, the company is developing two late-stage therapies, a second complement inhibitor and a copper-binding agent for Wilson disease. Alexion focuses its research efforts on novel molecules and targets in the complement cascade and its development efforts on the core therapeutic areas of hematology, nephrology, neurology, and metabolic disorders. Alexion has been named to the Forbes list of the World's Most Innovative Companies seven years in a row and is headquartered in Boston, Massachusetts' Innovation District. The company also has offices around the globe and serves patients in more than 50 countries.

Alexion's aspiration is to be the most rewarding place to work, where people are empowered to make a difference and where diversity of backgrounds and ideas is encouraged. We are looking for talented individuals who share our passion and commitment to change the lives of patients with rare diseases. We hope you will consider joining our team. Further information about Alexion can be found at: www.alexion.com.

As a leading employer in our industry, Alexion is proud to offer a highly competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more.