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Pfizer Scientist, Immunogenicity in Andover, Massachusetts

Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

As a Scientist in the Immunogenicity Sciences group within the Biomedicine Design Department (BMD), you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. You will work within the team and contribute to immunogenicity risk assessment of Pfizer biologics portfolio across a diverse array of modalities and disease areas.

You will have responsibility for maintaining and managing a human PBMC biobank and for contributing to the execution of lab-based predictive immunogenicity risk assessment strategies; notably conducting in vitro cellular assays.

You will work independently, use scientific judgment in making decisions within the area of your technical expertise, and propose new options and develop new processes to advance Immunogenicity Sciences knowledge and technology.

Your experience of applying knowledge of principles, concepts, and practices of cell-based immuno-assays will make you a critical member of the team. You are proactive in contributing to all team discussions and creating an environment of collaboration to achieve new milestones and help patients across the globe.

How You Will Achieve It

  • Primary responsibility for maintaining a human cell biobank (PBMC isolation and storage) in compliance with internal policies and aligned with best practices

  • Isolate and culture various blood-derived cell types to support the Immunogenicity team and BMD in delivering high-value data in support of Pfizer biologics portfolio

  • Design (work plan, timelines, deliverables), conduct and analyze results of immunogenicity in vitro assays to support the Pfizer biologics portfolio

  • Organize and present data to the immunogenicity team to inform decision making

  • Demonstrates innovative thinking to investigate and establish novel techniques or technologies to advance, improve or optimize scientific practices and automation

  • Effectively interact within Immunogenicity team and across BMD to support project advancement

  • Provides mentoring to other members of the team



  • MS with 3+ years industry experience in the field of biopharmaceuticals, leukocyte biology, applied health or immunology

  • Solid understanding of perturbations of the immune system in diseases as diverse as cancer and autoimmunity

  • Extensive hands-on experience with DC and/or T cell in vitro assays and flow cytometry

  • Track record of successful human PBMC isolation and storage

  • Ability to work under limited supervision

  • Ability to work and thrive in a highly matrixed organization

  • Proficiency in all common office and scientific software such as the Microsoft Office Suite and GraphPad Prism

  • Track record of scientific curiosity, initiative and ability to quickly learn and adapt to changing priorities

  • Outstanding organization and record-keeping skills

  • Excellent interpersonal relationship and communication skills


  • Experience with management of cell bank

  • Industry experience with a focus in biotherapeutics

  • Skills in other areas, such as LC-MS

  • Laboratory-based position requiring combination of sitting and standing

  • High attention to detail

  • Ability to analyze complex data


  • Eligible for Employee Referral Bonus: Yes

  • #LI-PFE

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development