Pfizer Scientist, Immunogenicity in Andover, Massachusetts
Why Patients Need You
Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.
What You Will Achieve
As a Scientist in the Immunogenicity Sciences group within the Biomedicine Design Department (BMD), you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. You will work within the team and contribute to immunogenicity risk assessment of Pfizer biologics portfolio across a diverse array of modalities and disease areas.
You will have responsibility for maintaining and managing a human PBMC biobank and for contributing to the execution of lab-based predictive immunogenicity risk assessment strategies; notably conducting in vitro cellular assays.
You will work independently, use scientific judgment in making decisions within the area of your technical expertise, and propose new options and develop new processes to advance Immunogenicity Sciences knowledge and technology.
Your experience of applying knowledge of principles, concepts, and practices of cell-based immuno-assays will make you a critical member of the team. You are proactive in contributing to all team discussions and creating an environment of collaboration to achieve new milestones and help patients across the globe.
How You Will Achieve It
Primary responsibility for maintaining a human cell biobank (PBMC isolation and storage) in compliance with internal policies and aligned with best practices
Isolate and culture various blood-derived cell types to support the Immunogenicity team and BMD in delivering high-value data in support of Pfizer biologics portfolio
Design (work plan, timelines, deliverables), conduct and analyze results of immunogenicity in vitro assays to support the Pfizer biologics portfolio
Organize and present data to the immunogenicity team to inform decision making
Demonstrates innovative thinking to investigate and establish novel techniques or technologies to advance, improve or optimize scientific practices and automation
Effectively interact within Immunogenicity team and across BMD to support project advancement
Provides mentoring to other members of the team
MS with 3+ years industry experience in the field of biopharmaceuticals, leukocyte biology, applied health or immunology
Solid understanding of perturbations of the immune system in diseases as diverse as cancer and autoimmunity
Extensive hands-on experience with DC and/or T cell in vitro assays and flow cytometry
Track record of successful human PBMC isolation and storage
Ability to work under limited supervision
Ability to work and thrive in a highly matrixed organization
Proficiency in all common office and scientific software such as the Microsoft Office Suite and GraphPad Prism
Track record of scientific curiosity, initiative and ability to quickly learn and adapt to changing priorities
Outstanding organization and record-keeping skills
Excellent interpersonal relationship and communication skills
Experience with management of cell bank
Industry experience with a focus in biotherapeutics
Skills in other areas, such as LC-MS
Laboratory-based position requiring combination of sitting and standing
High attention to detail
Ability to analyze complex data
Eligible for Employee Referral Bonus: Yes
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EEO & Employment Eligibility
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