AstraZeneca Pharmaceuticals LP Senior Scientist, Translational Science in Waltham, Massachusetts

Senior Scientist – Translational Science

At AstraZeneca, we work together across global boundaries to make an impact and find answers to challenges. We do this with the utmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe.


As a Senior Scientist for Oncology Translational Science at AstraZeneca R&D Boston/Waltham you will develop and implement assays to evaluate pharmacodynamics, mechanism of action and patient selection hypotheses using clinical samples. In this position, you will lead the analysis and work collaboratively with other members of the team to interpret the data. Knowledge of cancer biology and/or immuno-oncology and experience with a broad variety of cell and molecular biology techniques and platforms is required. You will be expected to work closely with your supervisor to define project goals, proactively seek information from the literature and internal resources to develop project plans, and deliver high-quality results in a timely manner.

Minimum Requirements:

  • BS/MS in Immunology, Oncology, Cell, Molecular Biology or equivalent, and 5 years experience, preferably in industry

  • Knowledge of cancer biology and/or immuno-oncology

  • Demonstrated expertise with proteomic/imuno-assays (ELISA, Western blot, mass spectrometry) and transcriptomic (RNASeq/Nanostring/qRTPCR, etc.)

  • Experience with analysis of clinical samples, including FFPE and frozen tissue; blood, plasma, serum

  • Knowledge of Microsoft office products (Word, Excel, PowerPoint)

  • Strong organizational, data management, and interpretation skills

  • Excellent communication skills

  • Effective presentation skills

  • A proven track record of high productivity and ability to work in a fast-paced environment

  • Capable of working collaboratively with other disciplines as well as independently when needed

Additional desirable expertise:

  • Experience with sample management databases

  • Experience with FACS and/or IHC

  • Experience with carrying out and analyzing multiplexed measurements

  • Experience working with human blood

  • Computational biology skills

AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious diseases. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're proud to have a unique workplace culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.

Next Steps – Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be a great fit, please share this posting with them.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.