Shire Global Program Management Lead in Cambridge, Massachusetts

The Global Program Management Lead (GPM) is responsible for managing the operational, planning, and decision-making processes in less complex Global Product Teams (GPT) and driving activities and being a team member in more complex GPTs at Shire. The GPM works closely with the Global Development Lead (GDL) and the Product Strategy Lead (PSL). The GPM also works to ensure the cross-functional teams operate effectively with positive Global team dynamics.

As a key member of GPT, the GPM is expected to be knowledgeable about the overall development program in order to be strategic in planning, team management and process management. The GPM achieves this by delivering high quality program management support and other high value services that supports the team and improves the probability of program success.

The GPM will be responsible for actively working with the GDL and PSL to manage the operational, planning and decision-making aspects of the GPT (generally, less complex programs) to ensure strong alignment between product strategy and operational execution.


80% of Time

The GPM works closely with EPT/LPT members to ensure timely completion of deliverables required to ensure robust and balanced cross-functional planning, decision-making, implementation and monitoring of global programs

  • Working closely with their manager and/or senior PM on the program but with minimal direct routine supervision responsible for providing best in class operations and program management.

  • Works with GDL/PSL to facilitate the elaboration, approval and execution of the global program strategy.

  • Coordinate and drive operational planning activities of the GPT including Strategic Product Plans (SPP), Target Product Profile, Long Range Plan, Life Cycle Management Plan, Geographical Expansion Plan, Business Cases, Competitive Landscape assessment and IP assessment ensuring alignment to program strategy.

  • Maintain the overall SPP

  • Collaborate with GDL, PSL and GPT functional team members to ensure coordinated evaluation of product opportunities/ scenarios and development of comprehensive integrated recommendations (e.g., to Governance Committees) and strategic and operational product plans based on program defined objectives and priorities.

  • Work independently to provide best-in-class operations and program management expertise to drive GPT members towards excellence in execution of plans i.e.

  • Develop, maintain and track robust, cross-functionally aligned program timelines (development and launches)

  • Facilitate collection, alignment and validation of program budget ensuring alignment to program strategy

  • Lead and facilitate cross-functional team meetings (agendas, minutes, tracking actions, etc.)

  • Facilitate team goal setting and tracking to ensure adherence to plan and strategy, and end of year team evaluation process

  • Develop and manage a program risk register

  • Coordinate GPT communications to ensure team member alignment

  • Issue and present reports to senior management on a routine basis

  • Promote visibility and transparency of information within the GPT, across GPT sub-teams and other forums to accelerate decision making, obtain alignment, and increase foundational knowledge, identify and communicate product and LPT related objectives, issues, risks, and where applicable, facilitate cross-GPT discussion on impact

  • Provide clear direction on product development requirements to meet expectations of external customers and business stakeholders

  • Facilitate preparations and analyses of GPT business reviews and routine evaluation processes, and progress against GPT strategy and action plans

  • Serve as strong objective advisor to GDL and PSL to maximize team effectiveness

  • Be responsible for making decisions regarding the appropriate risk when there is substantial program impact

  • Work with GDL/PSL to establish common decision processes & criteria for key decisions, e.g. go/no go criteria and stage-gate decisions.

  • Reinforce team operating principles to maximize alignment within the team and with other functions.

10% of Time

The GPM contributes to the development and execution of cross-business initiatives and processes.

0% - 10% of Time

Managing processes of defined scope required for effective program management (if appropriate)

Education and Experience

  • Minimum of 7+ years of experience in drug development in a pharmaceutical environment and/or Minimum of 5 years of cross-functional program management experience in managing a diversity of therapeutic areas and multiple stages of development and commercialization of prescription drug products.

  • Demonstrated ability to manage complex cross-functional teams and processes and work without routine supervision to deliver key accountabilities.

  • Strong understanding of the business environment and relevant key strategic and operational drivers. Project Management Professional (PMP) certification or equivalent proficiency a plus

  • Knowledge and understanding of global drug development and commercialization in the pharmaceutical industry.

  • Strong understanding and competency in planning processes and decision making

  • Demonstrated experience using standard program management tools and software including integrated development plans, timelines, risk management, and budget development and monitoring

  • BS in scientific discipline, or MBA with relevant pharmaceutical industry experience

Key Skills and Abilities

  • High level of accountability

  • Able to translate strategies into tangible deliverables for team to execute

  • Independent and creative thinker requiring minimum oversight. A self-starter who is pro-active, has tact and diplomacy, and is true team player

  • Strong interpersonal skills including cultural awareness and sensitivities, negotiation, managing meetings and group dynamics, conflict resolution, ability to balance concerns of line management with objectives of cross-functional team.

  • Strong ability to influence without authority and negotiate competing priorities

  • Significant experience working with and/or leading cross-functional and global teams and management and leadership of complex and cross-functional projects

  • Strong analytical and decision-making ability, including ability to synthesize complex and diverse inputs to a problem, and recommend solutions/preferred options and provide related budget and FTE impact.

  • Strong communication skills and presentation skills, including written and oral communication of executive level information and recommendations

  • Ability to provide insight into complex program interdependencies and assist in providing related budget and FTE impact

  • Pro-active with ability to adapt quickly and well to change, both organizationally and culturally

  • In-depth knowledge and use of Microsoft Project; demonstrated versatility in operations / program management tools to facilitate functional and geographic collaboration

  • Fluency (spoken and written) in English

Equal Employment Opportunity

Shire is an Equal Opportunity Employer committed to a diverse workforce. Shire will not discriminate against any worker or job applicant on the basis of race, color, religion, gender, national origin, ancestry, age, sexual orientation, marital or civil partnership status, pregnancy, gender reassignment, non-job related mental or physical disability, genetic information, veteran status, military service, application for military service, or membership in any other category protected under law.

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Reasonable Accommodations

Shire is committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please call 484-595-8400 and let us know the nature of your request and your contact information.

Shire is the leading global biotechnology company focused on serving people with rare diseases and other highly specialized conditions. We strive to develop best-in-class products, many of which are available in more than 100 countries, across core therapeutic areas including Hematology, Immunology, Neuroscience, Ophthalmics, Lysosomal Storage Disorders, Gastrointestinal/Internal Medicine/Endocrine and Hereditary Angioedema; and a growing franchise in Oncology.

Our employees come to work every day with a shared mission: to develop and deliver breakthrough therapies for the hundreds of millions of people in the world affected by rare diseases and other high-need conditions, and who lack effective therapies to live their lives to the fullest.